ETHYL-3-AMINO-1H-PYRAZOLE-4-CARBOXYLATE
Description:
Product Info:
- CAS Number： 6994-25-8
- Molecular Formula：C6H9N3O2
- Molecular Weight： 155.15g
- Synonyms: Ethyl 5-amino-1H-pyrazole-4-carboxylate, Ethyl 3-amino-4-pyrazolecarboxylate
It is an intermediate for Allopurinol and Repotrectinib. Allopurinol is a radical scavenger, a gout suppressant, an antimetabolite and an EC 1.17.3.2 (xanthine oxidase) inhibitor. Allopurinol is a xanthine oxidase enzyme inhibitor that is considered to be one of the most effective drugs used to decrease urate levels and is frequently used in the treatment of chronic gout.
Repotrectinib is a Kinase Inhibitor. The mechanism of action of repotrectinib is as a Proto-Oncogene Tyrosine-Protein Kinase ROS1 Inhibitor, and Tropomyosin Receptor Tyrosine Kinase A Inhibitor, and Tropomyosin Receptor Tyrosine Kinase B Inhibitor, and Tropomyosin Receptor Tyrosine Kinase C Inhibitor, and Cytochrome P450 3A4 Inducer. Repotrectinib is a next-generation tyrosine kinase inhibitor (TKI) specifically designed to address resistance in the treatment of non-small cell lung cancer (NSCLC), specifically due to mutations in the ROS1 gene.
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