Dapoxetine is a medicine used to treat a specific condition in men called premature ejaculation (PE). It is one of the very few medicines officially approved for this purpose. Its main goal is to help men gain better control over ejaculation and improve satisfaction with their sex life.
MAIN USES
Dapoxetine is often administered "on-demand" and is used to treat premature ejaculation. Depending on the person, the drug's effects might last anywhere from one to three hours. The effects are only meant to endure for that particular occasion and are thus transient. This eliminates the necessity for the body to take medicine continuously and permits spontaneity.
HOW DOES IT WORK
To understand how dapoxetine works, you need to know more about a chemical in the brain called serotonin. A neurotransmitter, such as serotonin, functions as a chemical messenger between nerve cells. It is involved in many things, including mood, happiness, and importantly, the body's reflex for ejaculation. Higher amounts of serotonin between nerve cells can help you delay ejaculate.
Dapoxetine belongs to a class of drugs known as Selective Serotonin Reuptake Inhibitors (SSRI). Its primary job is to slow down the reabsorption of serotonin in the brain. Dapoxetine blocks this reabsorption process. It allows serotonin to stay in the gap between nerve cells for a longer time. This prolonged serotonin signal helps to suppress the ejaculation reflex, giving a man more control and significantly increasing the time until ejaculation.
The key difference between dapoxetine and other SSRI is that it is absorbed very quickly and leaves the body very quickly. This makes it perfect for on-demand use for containing premature ejaculation, rather than needing to build up in the system over weeks.
IMPORTANT DRUG INTERACTIONS
Because dapoxetine affects serotonin and is processed by the liver, it can interact dangerously with many other medicines. It is absolutely crucial to tell your doctor about every other medicine, supplement, or herb you are taking. Key interactions include:
Other SSRIs and Psychiatric Medicine: You must NOT take dapoxetine if you are already taking other medicines for depression, anxiety, or other psychiatric disorders. Combining them can lead to a dangerous condition called Serotonin Syndrome, which causes confusion, agitation, rapid heart rate, and high body temperature.
Ergot Medicines: These medications are used to treat migraines. Mixing these with dapoxetine can cause a dangerous narrowing of blood vessels.
MAO Inhibitors (MAOIs): These are a different kind of antidepressant. Using dapoxetine with an MAOI or within 14 days of an MAOI-stop result can lead to serious potentially fatal effects.
Strong Painkillers: One should not use dapoxetine with strong prescription pain medicines such as tramadol or meperidine as this also elevates the chances of developing Serotonin Syndrome.
Other Medicines: Dapoxetine may have interactions with fungal, HIV/AIDS, and heart issues medicines. It may also help lower blood pressure and this may cause you to feel dizzy or faint when used together with other medicines that lower blood pressure.
Dapoxetine is a fast-acting pill that helps delay ejaculation by increasing a brain chemical called serotonin. Because it affects your brain chemistry, it can interact dangerously with many other drugs, so full disclosure with your doctor is essential for safe use.
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